Jelly, 21 bytes
“CSO“ANM“U“VZX”iⱮ€§ḅ-
A monadic Link accepting a list of characters which yields an integer.
How?
“CSO“ANM“U“VZX”iⱮ€§ḅ- - Link: list of characters, W
“CSO“ANM“U“VZX” - list of lists of characters = [['C','S','O'],['A','N','M'],['U'],['V','Z','X']]
€ - for each (L in those four lists):
Ɱ - map across (c in W) with:
i - first (1-based) index (of c in L) or 0 if not found
§ - sum each resulting list
- - literal minus one
ḅ - convert (the list of four sums) from base (-1)